‘Critical milestone’ in race for vaccine

By | April 1, 2020

The trials come as more than 4800 cases of coronavirus have now been confirmed across the country, with 2182 in New South Wales, 968 in Victoria, 781 in Queensland, 367 in South Australia, 392 in Western Australia, 69 in Tasmania, 84 in the Australian Capital Territory and 19 in the Northern Territory.

Twenty-one people have died, including two in WA, two in Queensland, 10 in NSW, four in Victoria, two in Tasmania and one in the ACT.

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Stranded tourists from Australia and New Zealand have boarded a chartered flight out of Nepal.

The Nepal Airlines flight had 222 Australians and 28 New Zealand citizens and permanent residents onboard and is scheduled to arrive in Brisbane on Thursday.

Passengers will face a 14-day quarantine upon arrival.

Nepal’s government has imposed a lockdown until April 7 halting flights, ordering vehicles off the roads, shutting down businesses and shuttering major markets.

Similar flights have rescued stranded German, French and US citizens out of Nepal in the past few days.

Nepal has reported five confirmed cases including one person who has recovered from it.

-AP

Australia’s national science agency has begun testing potential coronavirus vaccines in what has been described as a critical milestone in the global fight against COVID-19.

CSIRO scientists are performing the first stage of testing for two vaccine candidates at the agency’s high-containment biosecurity facility in Geelong.

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The pre-clinical trials, which are expected to take three months, will use animal subjects to test whether the potential vaccines from the University of Oxford and Inovio Pharmaceuticals are safe and effective.

The trials come as Australia’s COVID-19 cases have reached 4860 and Deputy Chief Medical Officer Paul Kelly has warned the virus won’t be beaten without a vaccine.

CSIRO chief executive Dr Larry Marshall has described the testing as a critical milestone, while health and biosecurity director Dr Rob Grenfell says it is very significant given the race by staff to get ready.

“Usually it takes one to two years to do this and we have apparently done it in eight weeks, so that’s actually really good,” Dr Grenfell told AAP.

The vaccine candidates were identified for CSIRO’s first trials by the Coalition for Epidemic Preparedness Innovations, in consultation with the World Health Organisation (WHO). They’re the first of a number the CSIRO hopes to test.

Dr Grenfell understands that one of the vaccine candidates is also being tested overseas and if it is shown to be safe and effective in both trials, there would be a rapid conversion into human trials.

“These types of studies are vital to give us the confidence to move into human studies,” he said.

Professor Trevor Drew, who leads CSIRO’s coronavirus and vaccine work, said they had been studying SARS CoV-2, which causes COVID-19, since January.

“We are carefully balancing operating at speed with the critical need for safety in response to this global public health emergency,” Professor Drew said in a statement.

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Dr Grenfell feels very optimistic about the fight against COVID-19 but said a vaccine was still a ways off, with suggestions it could be 18 months.

“The scientific ingenuity that we’re using, the global collaboration and co-operation is astounding,” he said.

“We’ve seen some momentous science across many avenues of the vaccine development pathway globally, so yes, I’m optimistic.

“At the moment, the best thing that we can all do is to maintain our social distancing and self-quarantining to minimise the spread whilst we’re waiting for effective drugs and vaccines.”

– AAP

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