Tag Archives: Defects

HMS researchers design algorithm that ID’s DNA defects, making more cancers treatable

Medications known as PARP inhibitors have emerged as a promising therapy for several forms of cancer fueled by a defect in the cells’ DNA repair machinery. Yet many people with cancers caused by the defect, known as HR deficiency, who stand to benefit from PARP inhibitors remain unidentified because standard genetic panels used in the… Read More »

Zika biomarkers in blood could lead to prenatal screening for birth defects

The highest risk of birth defects is from Zika virus infection during the first and second trimester, USC researcher says USC researchers have identified biomarkers associated with severe birth defects in babies born to women infected with the Zika virus. The discovery could lead to screening tests and a better understanding about how the infection… Read More »

Hispanic Women at High Risk for Neural Tube Defects, May Not Have Adequate Dietary Folic Acid

Because folate deficiency in pregnant women has been associated with an increased risk of neural tube defects, including anencephaly and spina bifida, it is recommended that all women take folic acid supplements before and during pregnancy.  In addition, the Food and Drug Administration (FDA) has required (since 1996) the addition of folic acid to many… Read More »