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A DDD is defined as the assumed average maintenance dose per day for a drug used for its main indication in adults. Safety of benzodiazepines and opioids in very severe respiratory disease: national prospective study. Given the unclear role of BZD in the management of refractory breathlessness, this study supports the suggestion that BZD should not be the first-line treatment for breathlessness in those with respiratory failure. Medicina B Aires. Drug Saf. Footnotes Disclosure The authors report no conflicts of interest in this work. First of all, male patients had a lower consumption of BZD than did the female patients for all levels of dispensing; they also consulted with fewer prescribers Table 3 and used fewer medication types than women Table 4. Benzodiazepine use in patients hospitalized in a department of internal medicine: frequency and clinical correlates. Abstract Background The common comorbidities associated with COPD include, among others, anxiety, depression, and insomnia, for which the typical treatment involves the use of benzodiazepines BZD.
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The DDD are determined on the basis of evaluation of the international use of the substance in question, bearing in mind that national therapy traditions indications, dosages often differ greatly. For BZD types, the coding is as follows: 1 one type; 2 2—3 types; and 3 more than three types. This work is published and licensed by Dove Medical Press Limited. In another study by Cohn et al 14 it was noted that a 30 mg dose of flurazepam resulted in a decreased tidal volume in mild COPD patients, and a decrease in oxygen saturation. Tell us more. Regression techniques were used to identify patient and clinical characteristics associated with BZD use. Postural instability and consequent falls and hip fractures associated with use of hypnotics in the elderly: a comparative review. The types of BZD included in the study were clonazepam, diazepam, oxazepam, alprazolam, nitrazepam, flunitrazepam, and midazolam.