hydromorphone (Dilaudid), insulin, labetalol (Trandate), lorazepam (Ativan), CONSIDERATIONS Route Onset Peak Duration BASELINE ASSESSMENT P0. Absorption in children is variable (23– 95%) and dose- dependent. Metabolism ROUTE. ONSET. PEAK. DURATION. PO, IM, IV. 4 – 7 days. 7 – 14 days. 21 days . arin, hydrocortisone, hydromorphone, imipenem/cilastatin, insulin, isoprotere- nol, ketorolac, leucovorin, levorphanol, lidocaine, linezolid, lorazepam, magne-. Apr 18, - More here on lorazepam duration of action, time in the body and Peak concentrations of lorazepam (20 ng/mL for a 2 mg dose) in I'm also on Zoloft and medicine for diabetes and high blood pressure and acid reflux.