A US study has concluded that weight gain is greater by around 2 to 4kg in HIV-positive people taking bictegravir or dolutegravir as part of their first antiretroviral therapy (ART), compared to their counterparts using other drug regimens. A similar effect was reported in those using the protease inhibitor darunavir. The study led by Dr… Read More »
People with HIV who already have resistance to a non-nucleoside reverse transcriptase inhibitor (NNRTI) when they start first-line antiretroviral treatment containing the integrase inhibitor dolutegravir were less likely to achieve viral suppression, a large clinical trial in South Africa has reported. NNRTI resistance has not been shown to affect responses to dolutegravir-based treatment previously. The… Read More »
There are higher rates of poor respiratory health in people ageing with HIV than in carefully matched HIV-negative people, with symptoms strongly associated with worse mental health and quality of life. Professor Caroline Sabin presented these data from the POPPY study to the virtual British HIV Association (BHIVA) conference yesterday. Higher rates of respiratory problems,… Read More »
A proactive, outreach-based service for people who inject drugs has successfully delivered the HIV prevention medication PrEP in the midst of Glasgow’s HIV outbreak, Dr Ceilidh Grimshaw of Sandyford told the virtual British HIV Association conference this week. Very few PrEP programmes for people who inject drugs have reported results and ongoing engagement with healthcare… Read More »
HIV incidence is below 0.1% per year among people who inject drugs in a large Vietnamese city, Professor Don Des Jarlais and colleagues report in the December issue of AIDS. They say the data clearly demonstrate that it is possible to achieve very low HIV incidence – ‘to end an HIV epidemic’ – among people… Read More »
As people living with HIV are living into old age, clinicians are developing new models of care. Dr Tom Levett and colleagues in Brighton, England, have recently described a combined HIV and geriatrics clinic – the Silver Clinic – that was designed to meet the needs of such patients by combining HIV care with geriatric… Read More »