Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels

Women are at increased risk for depressive symptoms during the menopause transition.  It has long been suspected that falling estrogen levels play a role in triggering the onset of depression; however, if all women experience declining levels of estrogen and progesterone during this transition, why is it that only some women suffer from depression in… Read More »

From Naysayer to Partner: How User Expectations and Needs Are Changing IT’s Role

Steven Goriah, VP of IT, CIO & CISO, Westchester Medical Center During the early weeks of the Covid-19 pandemic, there was a lot of focus on digital health, and the potential it had to improve patient care while increasing efficiency. But as leaders take a stock of how their teams responded — and how it… Read More »

ESMO: New Trodelvy breast, bladder cancer data show why Gilead’s going big for Immunomedics

Compared with the spate of multibillion-dollar buyouts last year, biopharma M&A has been relatively quiet in 2020—until last week, when Gilead Sciences surprised the market with its $ 21 billion purchase of Immunomedics. Now, two sets of new cancer data from Immunomedics’ first-in-class antibody-drug conjugate Trodelvy offer a glimpse into why Gilead paid such big money… Read More »

‘This is NOT a blip’: COVID-19 cases are accelerating in Canada. Should we be worried?

Article content continued With schools starting back up again and businesses largely open, the challenges are more difficult than in March or April, because we’re starting at a baseline of greater exposure risk, he said. “And I think people really need to recognize that.” In March, there was a “captive sense of fear” and dread,… Read More »

CDC reverses course again, says asymptomatic people should be tested

The Centers for Disease Control and Prevention reversed course again Friday, now recommending that people get tested if they come into contact with someone who has coronavirus, even if they are asymptomatic. “Due to the significance of asymptomatic and pre-symptomatic transmission, this guidance further reinforces the need to test asymptomatic persons, including close contacts of a… Read More »

Fat Hormone Influences Your Motivation to Eat

A new study helps to explain how leptin, a hormone produced by fat tissue, influences your motivation to eat. The researchers described for the first time a collection of leptin-responsive neurons in the brain’s lateral hypothalamic area (LHA). Those LHA neurons feed directly into the mesolimbic dopamine system, which controls the rewarding properties assigned to… Read More »