Tag Archives: Depression

Low-Dose Testosterone for Depression in Women: Does It Work?

In women, testosterone is produced by the ovaries in small amounts; however, levels of testosterone decline with age, independent of menopausal status. Low-dose testosterone has been used to improve sexual functioning in women with hypoactive sexual desire disorder.  In addition, other studies have shown that testosterone may improve fatigue and depressive symptoms.  However, these studies… Read More »

Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels

Women are at increased risk for depressive symptoms during the menopause transition.  It has long been suspected that falling estrogen levels play a role in triggering the onset of depression; however, if all women experience declining levels of estrogen and progesterone during this transition, why is it that only some women suffer from depression in… Read More »

Pilot Study of Neurosteroid Ganaxolone for Menopausal Depression

Over the last few years we have heard a great deal about neurosteroids, also known as neuroactive steroids.  This class of compounds are steroid hormones produced in the brain and endocrine tissues which can modulate neurotransmission.  Animal studies have demonstrated that neurosteroids have a broad range of activities, including antidepressant, anxiolytic, sedative, analgesic, anticonvulsant, neuroprotective,… Read More »

New Research Study: Pregnenolone Neurosteroid for the Treatment of Menopausal Depression

Over the last few years we have heard a great deal about neurosteroids, also known as neuroactive steroids.  This class of compounds are steroid hormones produced in the brain and endocrine tissues which can modulate neurotransmission.  Animal studies have demonstrated that neurosteroids have a broad range of activities, including antidepressant, anxiolytic, sedative, analgesic, anticonvulsant, neuroprotective,… Read More »